UNO took an early 6-2 lead, but LSU ripped off a 9-0 run in response and never looked back. They led by 22 at the half and were not threatened.
Khaleb Wilson-Rouse was the bright spot for New Orleans, dropping 21 points and five three pointers on the Tigers, as well as leading the team with 8 rebounds. Tyson Jackson added 14 points.
UNO will next be in action in the Big Easy Classic at Lakefront Arena beginning on Wednesday afternoon.